FGF23 and Marchiafava-Bignami disease: Recent studies have pointed out that not only CKD-MBD well-known biomarkers like phosphate, vit D, and PTH [3,5,7] but also novel and early ones like FGF23 are involved in the regulation, growth, and differentiation of cardiac myocytes being players in the pathogenesis of LVH [3,5,11,12].