GBA1 and Gaucher disease: Neurological Gaucher disease—while type 2 (acute neuronopathic) and type 3 (chronic neuronopathic forms) of Gaucher disease have been primarily associated with neurological manifestations, recently, mutations in β-glucocerebrosidase (Gcase) encoding gene GBA-1, have been associated in heterozygosity with a high recurrence of Parkinson’s disease (PD).