TP53 and cancer: Function-labeled miR-379 candidate target genes were primarily enriched in clusters associated with nutrition and energy regulation (FOXO and mTOR signaling pathways), cancer (melanoma, prostate cancer, p53 signaling, Hippo signaling, and transcriptional misregulation in cancer), and multi-functional cellular mechanisms or signaling pathways (cGMP-PKG signaling, focal adhesion, Hippo signaling pathway, pluripotency regulation in stem cells, TGF-beta signaling, and ubiquitin-mediated proteolysis) (Table 3).