Our previous study showed that a series of miRNAs mapped in the 14q32.2 maternally imprinted gene cluster region delineated by the delta-like homolog 1 and type III iodothyronine deiodinase genes (Dlk1-Dio3 mat) are related to NAFLD development and progression in a NAFL/NASH mouse model (fatty liver Shionogi [FLS] and mutated leptin gene transferred FLS ob/ob) [25]. The gene discussed is DLK1; the disease is metabolic dysfunction-associated steatohepatitis.