There are significant differences in drug medication (P=0.006), history of AUR (P ≤ 0.001), smoking (P=0.045), IPSS (P ≤ 0.001), IPP (P=0.006), PSA (P=0.047), RUV (P ≤ 0.001), QoL (P ≤ 0.001), and TPV (P=0.043) between the two groups; however, there is no significant difference in surgical methods (P=0.923), hypertension (P=0.181), diabetes (P=0.0916), drinking (P=0.437), urine culture (P=0.305), BMI (P=0.817), age (P=0.770), creatinine (Cr) (P=0.294), or operation time (P=0.931). This evidence concerns the gene KLK3 and Hypertension.