VEGFA and head and neck cancer: The RAS-activated phosphorylated Net (P-Net) can stimulate vascular endothelial growth factor (VEGF) expression and promotes angiogenesis, both of them are coexpressed in some tumors such as PCa, Kaposi's sarcoma and head and neck cancer, and more striking was that p-Net was highly expressed in tumor cells but not in normal surrounding tissue [20].