ELK3 belongs to the ETS oncogene family and plays an important role in many biological processes such as cell proliferation, migration, invasion, and angiogenesis [11–14], which has been proved to promote the progression of several types of tumors including breast cancer, liver cancer, and squamous cell carcinomas [11–13, 15, 31]. The gene discussed is ELK3; the disease is squamous cell carcinoma.