The effect of WAVE 3 expression level was investigated on the ability of AA to induce apoptosis of and inhibit invasion of breast cancer cells, it was studied whether AA interfered with proliferation and invasion of the cells by inhibiting WAVE 3 activation through the PI3K-AKT signaling pathway, and the MDA-MB-231 (F10) xenografted tumor in nude mice was established to investigate the antitumor activity of AA in vivo. This evidence concerns the gene PIK3CG and breast cancer.