VEGFA and age-related macular degeneration: Findings from the Ldl receptor−/− and Vldl receptor−/− mice enhance our understanding of the association between AMD and dysfunctional lipid metabolism by showing that the lack of LDL/VLDL in mice resulted in changes in the vascular endothelial growth factor (VEGF) expression and retinal neovascularization [178, 179].