This finding also concurs with its clinical relevance: 1) the normal lung tissues harbor significantly higher level of SIRT2 than NSCLC type (Figure S7A, data from GEO database GSE40275); 2) those high risk NSCLC patients possess much lower mRNA level of SIRT2 (Figure S7B). This evidence concerns the gene SIRT2 and non-small cell lung carcinoma.