SOX2 and metastatic malignant neoplasm in the lymph nodes: SOX2 expression was not associated with clinical stage, histological grade, tumor size, pT-stage, lymph node metastasis, and distal metastasis, which were in line with the previous publications regarding clinical stage [14, 35, 38], histological grade [14, 36, 41], tumor size [36], pT-stage [36, 38, 41], lymph node metastasis [14, 40], and distal metastasis [36].