In this regard, an intriguing hypothesis is that FAP degeneration to adipocyte‐like phenotype could contribute to myosteatosis, a common feature in patients affected by chronic inflammation and cachexia.31, 32 A detailed analysis of muscle biopsies obtained from cancer patients reported intramyocellular lipid droplets and large accumulation of neutral lipids in connective tissues in the rectus abdominis. Here, FAP is linked to cancer.