The 150 to 200 IL‐6 binding sites per B9 cell, corresponding to 75 to 100 functional IL‐6 receptors, is much lower than the number of IL‐6 receptors on hepatocytes and myeloma cells, which express several hundred to thousands of functional IL‐6 receptors.22, 26, 33. Here, IL6 is linked to plasma cell myeloma.