EGFR and neoplasm: The NIC values of the EGFR mutated tumours were significantly higher than those of the EGFR wild-type tumours in both the AP (0.18 ± 0.08 versus 0.13 ± 0.06, P = 0.032) and VP (0.47 ± 0.14 versus 0.37 ± 0.07, P < 0.001).