Notably, we found that high WBP5 levels correlated with elevated levels of several genes belonging to the HOXA and HOXB clusters; specifically, we observed a strong association with HOXA9 and HOXA10 and a moderate correlation with HOXA7. Many studies have demonstrated the importance of those genes in regulating the proliferation of haematopoietic cells and how their deregulation is paramount in driving the onset of myeloid leukaemias in vivo47–50. This evidence concerns the gene TCEAL9 and myeloid leukemia.