PTGDS (Prostaglandin D2 Synthase) and HPGD (15-Hydroxyprostaglandin Dehydrogenase) are enriched in the tumor region, while MGST3 (Microsomal Glutathione S-Transferase 3) is depleted in the tumor region in tissue section 1.2 (Figs. 4A and S4A). Here, HPGD is linked to neoplasm.