Importantly, fibrosis, as measured histologically (Figure 4, B, D, and E) and biochemically (Figure 4F), was comparable between C57BL/6 and fpr1–/– mice, suggesting that FPR-1 is not required for initiation or progression of liver fibrosis in response to CCl4 challenge. This evidence concerns the gene FPR1 and Hepatic fibrosis.