DLG1 is mainly identified as a tumor suppressor, since overexpression is observed early in the onset of cervical cancer (CeCa) [77] and elevated DLG1 promotes intestinal tumorigenesis [78], predicts poor prognosis in people with CRC [79] and increases the invasiveness of NSCLC cell lines [80]. This evidence concerns the gene DLG1 and colorectal carcinoma.