NUAK1 and cancer: In addition, miR-204-5p serves as a cancer suppressor gene by modulating oncogenic Wnt/FZD signaling pathways [62], inhibiting NUAK family kinase 1 (NUAK1) in NSCLC [59], and mediating a long-noncoding RNA (lncRNA) MALAT1 effect on the epithelial-to-mesenchymal transition (EMT) and cells invasion [63].