However, some molecular markers have been identified, that provide information on perineural (EGFR) recurrence and invasion (Silva Amâncio et al., 2017) epithelial-mesenchymal transition (E-cadherin and Vimentin) (Da Cunha et al., 2016) and lymph node metastasis (miR-101, miR-1, and miR-204) (Hartz et al., 2016). The gene discussed is CDH1; the disease is metastasis.