Evaluation of serologic markers for atrophic gastritis, such as gastrin-17, pepsinogen-1, pepsinogen-2, the pepsinogen-1/pepsinogen-2 ratio was developed by Biohit; however, this evaluation did not allow us to determin the degree of stomach mucous membrane atrophy in cases of atrophic gastritis. This evidence concerns the gene GAST and chronic atrophic gastritis.