Potential CD is characterized by the presence of CD specific autoantibodies in sera (patients enrolled to our study had positive celiac specific autoantibodies both anti-tTG2-IgA and anti-EMA-IgA) and normal histology of the small intestine (described as Marsh 0 in modified Marsh–Oberhuber classification) or only increased number of IEL without other features of inflammation (described as Marsh 1). This evidence concerns the gene CD79A and Cowden disease.