In the IMQ induced psoriasis-like mice, (R)-Salbutamol administration reduced the expression of IL-17 in plasma along with a downregulation of the CD4+ Th17+ T cells (Th17) and upregulation of the CD3+CD4+ T cells and CD25+ Foxp3+ Tregs in the spleens. The gene discussed is CD4; the disease is psoriasis.