Assessing different splenic immunological factors indicated that exposure to these mycotoxins led to increased IL-4 mRNA levels, oxidative stress, and immunotoxicity in the spleen [46] whereas the combined LAB treatment with AFB1 or FB1 suppressed and normalized mRNA levels of IL-4, showing protective effects induced by LAB against AFB1 and FB1 via diminishing toxin adhesion and bioavailability [46]. The gene discussed is IL4; the disease is immune system toxicity.