To expand the inventory of available translational Disc1 models, we recently reported a novel rat short genetic variant model of DISC1 truncation (Disc1 svΔ2), which lacks exons 2–13 following targeted deletion with CRISPR/Cas9 [26] and thus recapitulates clinically observed early DISC1 truncations associated with schizophrenia [27]. The gene discussed is DISC1; the disease is schizophrenia.