Other compounds of Stevia pilosa and Stevia eupatoria include β-sitosterol and stigmasterol, which have an antiproliferative effect by activating the extracellular receptor kinase (ERK) 1/2 pathway, and apoptosis induction, decreasing Bcl-2 expression and increasing BAX expression in breast cancer cells MDA-MB-231 [22]. The gene discussed is BAX; the disease is breast cancer.