In support of a role for viral infection in the modulation of VF susceptibility, a common variant genome-wide association study in the Dutch AGNES population, which compared individuals with and without VF in the setting of a first acute STEMI,[16] identified a VF susceptibility locus at chromosome 21q21 (rs2824292) close to the CXADR gene. This evidence concerns the gene CXADR and viral infectious disease.