BRD4 and malignant colon neoplasm: Besides, miR‐377 was also confirmed to inhibit proliferation and invasion of cervical cancer cells by regulating the expression of Zinc Finger E‐box‐Binding Homeobox 2.14 In gastric cancer, it was also found to repress the expression of VEGFA and then suppress proliferation and metastasis of cells.15 Besides, BRD4 was confirmed to be frequently down‐regulated by aberrant promoter hypermethylation in human colon cancer in previous study.16 BRD was found to be negatively related to miR‐377 in our pre‐experiment.