Human germinal center‐associated lymphoma (HGAL) is a B‐cell specific marker the expression of which is observed in the cytoplasm of normal germinal center B cells and lymphomas of GCB derivation.40 Gualco et al reported that the inclusion of HGAL in the Hans immunohistological algorithm improved the detection of the GCB subtype of DLBCL.41 In our study, the HGAL staining results matched those predicted by the Hans model in 82% (9/11) of cases. This evidence concerns the gene GCSAM and diffuse large B-cell lymphoma.