Neutrophil gelatinase‐associated lipocalin (NGAL), a member of the lipocalin family, is a low molecular weight secretion protein originally found in activated neutrophils.3 There is growing evidence that urinary NGAL can mirror the kidney function damage of cirrhotic patients with acute kidney injury (AKI).4, 5 Intriguingly, Huelin et al6 discovered that urinary NGAL could differentiate the classification of acute tubular necrosis; continuous elevated NGAL is associated with the progression of AKI, which was a predictive factor of 28‐day mortality in the latest research. The gene discussed is LCN2; the disease is acute kidney tubular necrosis.