Three prospective studies reported that systemic IL‐6 levels are positively correlated with the development of early AMD,218 progression to late AMD,219 and faster GA growth.220 Other interleukins, including IL‐1 β, IL‐8, and IL‐10, have also been studied in AMD, though to a lesser extent, and no relation has been found between these other interleukins and disease progression in AMD.220. This evidence concerns the gene IL10 and age-related macular degeneration.