AKT1 and pancreatitis: When PI3K inhibitor Wortmannin was given in advance and then PAAF was injected into the abdominal cavity, the phosphorylation level of AKT and expression of NF-kB were notably reduced compared with the PAAF treating only, and the number of pancreatic cell apoptosis was significantly increased, while the aggravation of pancreatitis was not obvious.