AKT1 and acute pancreatitis: The phosphorylation levels of PI3K and AKT and the expression of NF-kB were significantly lower after APD treatment, indicating that APD inhibited PI3K/AKT signaling pathway, thereby reducing the involvement of downstream NF-kB in the nucleus and reducing the inhibition on pancreatic cell apoptosis, and ultimately exerted a role in the treatment of acute pancreatitis.