Wang X et al. reported that embryonic fibroblasts derived from FUT8-null mice significantly suppressed cell proliferation by inhibiting core fucosylation of EGFR [36] and Wang Y et al. reported that a FUT8 gene deficiency resulted in the attenuation of responses to epidermal growth factor and hepatocyte growth factor in a human liver cancer-derived cell line HepG2 [37]. This evidence concerns the gene FUT8 and liver cancer.