The most vital module for miR-200c network including 15 nodes and 86 edges, which were highly associated with pathways in cancer, FoxO signaling pathway, miRNAs in cancer, PI3K-Akt signaling pathway, proteoglycans in cancer, Viral carcinogenesis, HIF-1 signaling pathway, cell cycle, and p53 signaling pathway. The gene discussed is TP53; the disease is cancer.