Other genes, such as BCORL1 (OVA_003), CASP3 (OVA_047), CHD2 (OVA_013), FAT3 (OVA_365) and LZTR1 (OVA_378), were heterogeneous, having differing clonality in the primary versus the metastatic tumours. The gene discussed is CASP3; the disease is metastatic neoplasm.