In contrast, we reported a total of nine actionable genes across the cohort, including genes NFKBIA, IGF1R, MYC, MCL1, PIK3CA, ALK, CCND2, CCND3 and CDK6. Only three genes, including MCL1 (OVA_378), MYC and PIK3CA (OVA_003), were found to be clinically actionable in both primary HGSOC and metastatic tumours. This evidence concerns the gene PIK3CA and metastatic neoplasm.