CAPN2 and chronic obstructive pulmonary disease: The first gene with the highest module membership in module 2 is CAPN2 that is down-regulated in COPD cases (Fold-change = 0.8 and FDR = \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$7.3\,\cdot {10}^{-7}$$\end{document}7.3⋅10−7) and encodes the large subunit of the calcium-activated neutral protease calpain 2.