NFKB1 and chronic obstructive pulmonary disease: We found that the COPD correlation network built by SWIM software consists of three modules, of which one includes multiple switch genes and is significantly enriched in pathways like: B cell receptor signaling pathway, NF-kappa B (NF-κB) signaling pathway, hypoxia, regulation of inflammatory response, regulation of immune response, collagen fibril organization, regulation of TGFB production, and extracellular matrix organization.