FOLH1 and posterior cortical atrophy: PSMA, an integral membrane glycoprotein expressed 100–1000 fold on membranes of PCa cells compared to prostate cells, has been shown to correlate with aggressive disease, disease recurrence, and metastasis12–14, and radio-tracer targeting of PSMA in conjunction with CT has been shown in a systematic review and meta-analysis of 5 studies to predict LNI with a sensitivity and specificity of 80% and 97% respectively15.