NAPRT and acute myeloid leukemia: Equally, we cannot rule out the possibility that a variant is private to a particular family; we would have overlooked the candidacy of NAPRT1 in FML064 (p.Val216_Phe219dup) were it not for another variant (p.Arg405*) being recently reported in the same gene in an MDS/AML family by the group of Patnaik et al.41.