Following the recent study describing a synonymous GATA2 germline variant affecting RNA splicing in a MDS/AML family45, for completeness, we also performed an in silico analysis of our WES results using the Annovar tool46 and the RefSeq Database47 identifying 39 novel splicing synonymous variants (Supplementary Data 9), none of which arose in either GATA2 or any other Group 1 loci. The gene discussed is GATA2; the disease is myelodysplastic syndrome.