S100B and cavernous hemangioma: Finally, a small study in 2016 by Linsenmaier et al. using the Elecsys S100B assay showed in 41 mTBI patients that while all 29 CT-negative scans were 1.5 T MRI-negative, of the 12 CT+ scans, only five were MRI+; six were false positives, and one was a cavernous angioma (nontraumatic) [11].