S100A8 and metastatic neoplasm: In line, the S100A8/CRP abundance ratio was again found significantly up-regulated in the group of patients with OSD > 1000 as calculated from proteomics data of metastatic tumors isolated from HGSOC patients combining the study by Coscia et al. [50] and a more recent study by Eckert et al. (Figure 5G,H, n = 36) [51] Kaplan–Meier analysis confirmed that patients with an S100A8/CRP abundance ratio equal or above a cutoff value of 3.038 showed a significantly longer overall survival time compared to patients with values below this cutoff (Figure 5I).