EPO and perinatal asphyxia: Elmadhy et al. 2010 [116] (Table 3) recruited 45 neonates and divided them into three groups: (a) 15 normal infants, (b) 15 infants affected with HIE and receiving only conventional treatment (control) and (c) 15 infants affected by HIE who were treated by conventional treatment plus five daily doses of subcutaneous r-Hu-EPO, with the first dose given within 4–6 h after birth followed by four daily doses [116].