High levels of glucose transporter 1 (GLUT1, gene symbol SLC2A1) have been found in several cancers, including intrahepatic CCA (iCCA), associated with hypoxia, which is consistent with the elevation of anaerobic metabolism together with the poor cell differentiation and metastasis that are characteristic of these tumors [16]. The gene discussed is SLC2A1; the disease is cholangiocarcinoma.