Among members of the family ABCB of the ABC proteins, the high expression of P-glycoprotein or multidrug resistance protein 1 (MDR1, gene symbol ABCB1) detected by immunohistochemistry in HCC was associated with a bad prognosis [24,25]; moreover, this pump has been proposed as a valuable biomarker of prognosis in gallbladder cancer [26]. Here, ABCB1 is linked to hepatocellular carcinoma.