PTPN1 and cancer: To investigate the activity of PTP1B in the pro-invasive and metastatic processes induced by IL-13 in cancer cells, we prepared KM12SM/SW620 CRC cells, U118/U87 GBM cells and A2780/SKOV3 OC cells PTP1B-silenced using two different siRNAs (Figure 3A, Supplementary Figure S2A).