For hSCAP activity-related marker expression, BD reported a significant up-regulation of a series of osteogenic/odontogenic (DSPP [33,36]; ALP [34]; BSP [33], DMP-1, MEPE [36]) and angiogenic (TGFβ1 [39]) markers when compared to PR MTA, while producing a significantly lower up-regulation of other osteogenic/odontogenic markers (OCN [33,36]; OSX, DSPP [33]; BSP [34]) and angiogenic growth factors (ANGPT-1, FGF2 [39]). Here, IBSP is linked to Behcet disease.