CSF2 and vesiculobullous skin disease: Yamauchi et al. identified numerous candidate biomarkers that were correlated with the development of bullous keratopathy and low endothelial cell density, including IL-1a, IL-8, IL-17A, TNF-a, granulocyte-macrophage colony-stimulating factor (GM-CSF), macrophage inflammatory protein (MIP)-1a, IFN-c, and E-selectin levels in the AqH [31].