In addition, as expected, TP53 mutations were strongly associated with non-endometrioid histology (p < 0.001) and with high-grade carcinomas (p < 0.001), whereas PI3KCA, CTNNB1, PTEN, and KRAS were mainly found altered in endometrioid carcinomas. The gene discussed is PTEN; the disease is endometrioid adenocarcinoma.