Muscle atrophy can be triggered by treatment with dexamethasone (DEX) or muscle disuse, which accelerate muscle protein degradation through induction of muscle specific ubiquitin ligases MAFbx/Atrogin‐1 and MuRF1.45 We next examined the effects of indoprofen on the DEX‐mediated myotube atrophy. The gene discussed is TRIM63; the disease is Atrophy.