The enrichment of 11 KEGG pathways of immune function is the C-type lectin receptor signaling pathway (p=0.004), Kaposi sarcoma-associated herpesvirus infection (p=0.012), human papillomavirus infection (p=0.019), human immunodeficiency virus 1 infection (p=0.020), TNF signaling pathway (p=0.026), human cytomegalovirus infection (p=0.027), Pertussis (p=0.042), Herpes simplex virus 1 infection (p=0.002), Inflammatory mediator regulation of TRP channels (p=0.020), Toll-like receptor signaling pathway (p=0.021), Fluid shear stress and atherosclerosis (p=0.045). The gene discussed is TNF; the disease is human papilloma virus infection.