Therefore, we examined the mRNA and protein expression of SOCS1 in QSG-7701 cells and 7 different HCC cell lines (SMMC-7721, MHCC-97H, Hep3B, HepG2, Huh7, HCC-LM3 and SK-Hep-1). The gene discussed is SOCS1; the disease is hepatocellular carcinoma.