Upregulated DEGs were predominantly enriched in “Legionellosis,” “Transcriptional misregulation in cancer” and “Pathways in cancer” in KEGG_PATHWAY analysis, and “Viral RNP Complexes in the Host Cell Nucleus”, “Chemokine receptors bind chemokines,” and “Binding of TCF/LEF:CTNNB1 to target gene promoters” in REACTOME_PATHWAY analysis (Table 3). The gene discussed is HNF4A; the disease is legionellosis.