FBN1 and Marfan syndrome: The group of Dr Huang at ShangaiTech University used a new CRISPR method, the recently developed base editing (discussed in the previous section) to correct a single base in the FBN1 gene involved in the Marfan syndrome, a rare autosomal dominant disorder in heterozygous embryos.169 The embryos were obtained by injecting sperm from a patient with Marfan syndrome into a mature oocyte.