Compared to clinicopathological features, including tumor size, tumor location, adjuvant chemotherapy and pTNM stage, CD66+ (hazard ratio [HR] = 1.546; 95% CI = (1.055‐2.268); P = .026) and α‐SMA+ cells (HR = 2.212; 95% CI = 1.493‐3.278; P < .001) were independent factors for DFS in GAC. The gene discussed is ACTA1; the disease is neoplasm.