TGFB1 and neoplasm: Blocking TGF‐β causes a conversion from the procancer phenotype to the anticancer subtype, suggesting that the TAN categorization paradigm resembles the M1/M2‐subtype paradigm of tumor‐associated macrophages.14, 38 In this study, a high density of TANs in a GAC specimen was associated with a poor clinical outcome and likewise demonstrated that N2‐type neutrophils might be the major cellular phenotype in GAC tissue, despite there being no particular factors that can be applied to discriminate the N1/N2 subsets.