EGFR and asthma: To relate these findings to human asthma, transcriptomic analysis of epithelial brushings from human volunteers identified a cluster of severe asthmatics displaying eosinophilia and neutrophilia with increased expression several EGFR ligands and ERBB3 whose protein product is known to form heterodimers and signal with EGFR.40 Importantly, epithelial expression of IL13 was found within a sub‐cluster of these asthmatic subjects, suggesting that our transgenic mouse model, which expresses IL‐13 in the airway epithelium, mirrors a sub‐phenotype of the human disease.