In the published work, release of IL‐13 following wounding was shown to enhance epithelial repair via HB‐EGF.62 Thus, it is significant that IL13 expression in the U‐BIOPRED severe asthma cluster closely mirrored epithelial HBEGF expression suggesting a wound healing response in this subgroup of patients involving an IL‐13/HB‐EGF/EGFR axis. This evidence concerns the gene GSTM1 and asthma.